Vascular Calcification in Chronic Renal Failure

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Vascular Calcification in Chronic Renal Failure

Accelerated atherosclerotic plaque calcification and extensive medial calcifications are common and highly detrimental complications of chronic kidney disease. Valid murine models have been developed to investigate both pathologically distinguishable complications, which allow for better insight into the cellular mechanisms underlying these vascular pathologies and evaluation of compounds that ...

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Vascular calcification in chronic renal failure.

The prevalence and extent of vascular calcification (VC) increases rapidly with time on dialysis. There is increasing evidence that medial calcification of conduit arteries, without intimal disease, is associated with important abnormalities of vascular compliance and increased risk of cardiovascular death. Coronary artery calcification is also common in end-stage renal disease, but further res...

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Mitral anular calcification in chronic renal failure.

In order to determine the incidence and pathogenesis of mitral anular calcification (MAC) in chronic renal failure, we analyzed biochemical, hemodynamic and echocardiographic data in 168 patients on long-term hemodialysis. Mitral anular calcification is more common in patients with chronic renal failure than in other patients of similar age. Its pathogenesis appears to be due to abnormal calciu...

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Metastatic Calcification in Chronic Renal Failure

involvement of the upper zones. There was also dense pleural thickening noted along the posterior margins extending from the apical region inferiorly up to the basal region. Pleural calcification was also noted in the left apical region posteriorly. Findings were secondary to metastatic calcification secondary to renal failure/hemodialysis. There were also discrete small areas of calcification ...

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Perineurial and vascular calcification in a patient with chronic renal failure.

Sir, The term calciphylaxis, coined by Seyle in 1962 (1), traditionally describes an uncommon entity that usually presents with cutaneous necrosis due to small vessel calcification. As the original concept regarding risk factors for the disease has changed considerably in the past few years, we have recently suggested the term ‘cutaneous vascular calcification’ for this pathology, based on the ...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 2011

ISSN: 0009-7330,1524-4571

DOI: 10.1161/circresaha.110.225904